Construction work for the radical overhaul of Highbury Corner will begin on Thursday next week.
The work is expected to continue until late next year and Transport for London (TfL) has advised people to leave more time for their journeys.
As revealed by the Gazette in March, the revamp will shift the emphasis away from motorists and towards pedestrians and cyclists.
Much of the area outside Highbury and Islington station will be pedestrianised and turned into a public space.
The “intimidating” 1960s roundabout will be removed and replaced with two-way roads, with the installation of segregated cycle lanes on all three remaining sides of the roundabout.
Heidi Alexander, Sadiq Khan’s deputy mayor for transport, said: “I’m delighted work is getting underway on these plans that will improve safety and improve the environment for everyone who uses Highbury Corner.
“With more segregated cycle lanes across the junction, improved pedestrian crossings and a new public space, the transformed junction will encourage even more people to walk and cycle as part of their everyday routine.”
Nick Kocharhook a committee member of Cycle Islington, said: “Many people on bicycles do their best to avoid Highbury Corner today. The new junction layout will be a huge improvement for adults and children of all ages.
“We are confident that these cycle tracks will be just as popular as others installed over the past five years in London. We can’t wait to cycle on the new design as soon as it’s finished!”
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